Diastereocontrol in Asymmetric Allyl–Allyl Cross-Coupling: Stereocontrolled Reaction of Prochiral Allylboronates with Prochiral Allyl Chlorides
نویسندگان
چکیده
منابع مشابه
Baker's yeast catalyzed asymmetric reduction of prochiral ketones in different reaction mediums
Baker’s yeast catalyzes the asymmetric reduction of prochiral ketones in water and in various organic solvents. The reaction in water, which is the first solvent of choice for bio-reactions, led to a high product yield and enantiomeric excess, but the low miscibility of organic molecules in water resulted in lower conversions when more hydrophobic ketones were used. Petroleum-based solvents suc...
متن کاملChiral phase-transfer catalysis in the asymmetric α-heterofunctionalization of prochiral nucleophiles
Chiral phase-transfer catalysis is one of the major catalytic principles in asymmetric catalysis. A broad variety of different catalysts and their use for challenging applications have been reported over the last decades. Besides asymmetric C-C bond forming reactions the use of chiral phase-transfer catalysts for enantioselective α-heterofunctionalization reactions of prochiral nucleophiles bec...
متن کاملCatalytic Enantioselective Alkylation of Prochiral Ketone Enolates
The synthesis of stereogenic all-carbon quaternary centers remains a formidable challenge, notwithstanding the strides made by modern organic chemistry in this regard [1]. Contemporary advances in enolate alkylation havemade it a fundamental strategy for the construction of C–C bonds [2]. Although methods for the reaction of a number of enolate types (e.g., ester, ketone, and propionimide) with...
متن کاملConstruction of Tertiary Chiral Centers by Pd-catalyzed Asymmetric Allylic Alkylation of Prochiral Enolate Equivalents.
The palladium-catalyzed decarboxylative allylic alkylation of enol carbonates derived from lactams and ketones is described. Employing these substrates with an electronically tuned Pd catalyst system trisubstituted chiral centers are produced. These stereocenters have been previously challenging to achieve using Pd complex/chiral P-N ligand systems.
متن کاملNickel-catalyzed coupling of allyl chlorides and enynes.
The Ni-catalyzed coupling of allyl chlorides and enynes has been developed; the cyclization of enynes was triggered by the addition of pi-allylnickel species to the alkyne part, followed by the incorporation of the alkene part.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2011
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja2075967